A theoretical validation of the B-matrix spatial distribution approach to diffusion tensor imaging
PBN-AR
Instytucja
Wydział Fizyki i Informatyki Stosowanej (Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie)
Informacje podstawowe
Główny język publikacji
EN
Czasopismo
Magnetic Resonance Imaging
ISSN
0730-725X
EISSN
1873-5894
Wydawca
Elsevier Science Inc.
Rok publikacji
2016
Numer zeszytu
Strony od-do
1--6
Numer tomu
36
Link do pełnego tekstu
Identyfikator DOI
Liczba arkuszy
0.42
Autorzy
Pozostali autorzy
+ 1
Słowa kluczowe
EN
diffusion
anisotropy
MRI
DTI
phantoms
Streszczenia
Język
EN
Treść
The recently presented B-matrix Spatial Distribution (BSD) approach is a calibration technique which derives the actual distribution of the B-matrix in space. It is claimed that taking into account the spatial variability of the B-matrix improves the accuracy of diffusion tensor imaging (DTI). The purpose of this study is to verify this approach theoretically through computer simulations. Assuming three different spatial distributions of the B-matrix, diffusion weighted signals were calculated for the six orientations of a model anisotropic phantom. Subsequently two variants of the BSD calibration were performed for each of the three cases; one with the assumption of high uniformity of the model phantom (uBSD-DTI) and the other taking into account imperfections in phantom structure (BSD-DTI). Several cases of varying degrees of phantom uniformity were analyzed and the distributions of the B-matrix obtained were used for the calculation of the diffusion tensor of a model isotropic phantom. The results were compared with standard diffusion tensor calculation. The simulations confirmed the improvement of accuracy in the determination of the diffusion tensor after the calibration. BSD-DTI improves accuracy independent of both the degree of uniformity of the phantom and the inhomogeneity of the B-matrix. In cases of a relatively good uniformity of the phantom and minor distortions in the spatial distribution of the B-matrix, the uBSD-DTI approach is sufficient. © 2016 Elsevier Inc.
Cechy publikacji
original article
peer-reviewed
Inne
System-identifier
idp:102615
CrossrefMetadata from Crossref logo
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