Abnormalities in lung volumes and airflow in children with newly diagnosed connective tissue disease.
PBN-AR
Instytucja
Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji im. prof. dr hab. med. Eleonory Reicher
Informacje podstawowe
Główny język publikacji
angielski
Czasopismo
Pneumonologia i Alergologia Polska
ISSN
0867-7077
EISSN
2299-8292
Wydawca
VM Media sp. z o.o. VM Group sp. k. Grupa Via Medica
DOI
Rok publikacji
2016
Numer zeszytu
Strony od-do
22-28
Numer tomu
84
Identyfikator DOI
Liczba arkuszy
0,6
Autorzy
Pozostali autorzy
+ 4
Słowa kluczowe
angielski
lung function tests, rheumatic diseases of childhood, pulmonary involvement
Streszczenia
Język
angielski
Treść
Introduction: Connective tissue diseases (CTDs) of childhood are rare inflammatory disorders, involving various organs and tissues including respiratory system. Pulmonary involvement in patients with CTDs is uncommon but may cause functional impairment. Data on prevalence and type of lung function abnormalities in children with CTDs are scarce. Thus, the aim of this study was to asses pulmonary functional status in children with newly diagnosed CTD and follow the results after two years of the disease course. Material and methods: There were 98 children (mean age: 13 ± 3; 76 girls), treated in Department of Pediatric Rheumatology, In - stitute of Rheumatology, Warsaw and 80 aged-matched, healthy controls (mean age 12.7 ± 2.4; 50 girls) included into the study. Study procedures included medical history, physical examination, chest radiograph and PFT (spirometry and whole body-plethy- smography). Then, the assessment of PFT was performed after 24 months. Results: FEV 1 , FEV 1 /FVC and MEF50 were significantly lower in CTD as compared to control group, there was no difference in FVC and TLC. The proportion of patients with abnormal lung function was significantly higher in the study group, 41 (42%) vs 9 (11%). 24-months observation didn’t reveal progression in lung function impairment. Conclusions: Lung function impairment is relatively common in children with CTDs. Although restrictive ventilatory pattern is considered typical feature of lung involvement in CTDs, airflow limitation co uld also be an initial abnormality
Inne
System-identifier
PX-571dcde0c2dc688670181c8f
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